Emollient creams for face and body improve eczema in children with atopic dermatitis and help to restablish the normal skin flora

Barrier Repair Therapy in Atopic Eczema: effects of isoleucine, rhamnosoft and niacinamide facial and body creams on clinical, itch and Staphylococcus aureus skin colonization: A prospective assessor-blinbed study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN24922464

Enrollment

Registered

2015-10-16

Start date

2015-01-02

Completion date

Unknown

Last updated

2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic Eczema Skin and Connective Tissue Diseases Atopic Eczema

Interventions

Participants are provided with two products concurrently to apply twice daily for 8 consecutive weeks: 1. Participants apply 2 Finger Tip Units (1g) of the Nutratopic pro-AMP facial c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged between 2 and 18 years 2. Mild to moderate atopic eczema according to Hanifin diagnostic criteria

Exclusion criteria

Exclusion criteria: 1. Severe form of atopic eczema 2. Use of corticosteroids, calcineurin inhibitors or systemic or topical antibiotics in the 4 weeks prior to enrollement

Design outcomes

Primary

Measure	Time frame
1. Eczema severity is measured using the Eczema Severity Index score (4-point scale) at baseline, week 4 and week 8 2. Itch intensity evaluated by a 10-cm Visual Analogue Scale at baseline, week 4 and week 8	—

Secondary

Measure	Time frame
Staphylococcus aureus skin colonization is obtained from lesions using skin swabs at baseline and 2 months.	—

Countries

Italy

Contacts

Public ContactMassimo Milani

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026