At cancer diagnosis ? A ?window of opportunity? for behavioural change towards physical activity for colon and breast cancer patients

Conditions

Colon and breast cancers receiving adjuvant chemotherapy Cancer Malignant neoplasm of colon and breast

Lis Adamsen, Christina Andersen, Christian Lillelund, Kira Bloomquist, Tom Møller

BMJ Open2017-08-0131 citations

10.1136/bmjopen-2017-016689

The challenge of preserving cardiorespiratory fitness in physically inactive patients with colon or breast cancer during adjuvant chemotherapy: a randomised feasibility study

Tom Møller, Christian Lillelund, Christina Andersen, Kira Bloomquist, Karl Bang Christensen et al. (11 authors)

BMJ Open Sport & Exercise Medicine2015-10-0138 citations

10.1136/bmjsem-2015-000021

At cancer diagnosis: a ‘window of opportunity’ for behavioural change towards physical activity. A randomised feasibility study in patients with colon and breast cancer

Tom Møller, Christian Lillelund, Christina Andersen, Bent Ejlertsen, Lone Nikoline Nørgaard et al. (11 authors)

BMJ Open2013-11-0132 citations

10.1136/bmjopen-2013-003556

Interventions

Two interventions are tested with a comparable control group. All study group participants receives the oncologists advice of meeting national recommendations for physical activity. The two interventi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with breast cancer (stage I - III) or colon cancer (stage II and III) in adjuvant chemotherapy 2. WHO performance status of 0 or 1 3. Aged 18 + years who do not meet criteria for recommended physical activity levels of 150 min/week of moderate leisure time physical activity, and exercises at least 20 minutes of strenuous physical activity twice a week

Exclusion criteria

Exclusion criteria: 1. Patients with myocardial infarction within the past three months 2. Symptomatic heart failure 3. Angina pectoris 4. Abnormal pathological ECG

Design outcomes

Primary

Measure	Time frame
Maximum oxygen uptake - VO2-peak measured baseline and at 6, 12 and 39 weeks	—

Secondary

Measure	Time frame
1. Dual Energy X-ray Absorptiometry / DXA scan (Baseline and 12 weeks) 2. Muscular strength (baseline and at 6, 12 and 39 weeks) 3. Blood cholesterols (baseline, 12 and 39 weeks) 4. Blood pressure, pulse (baseline and 6, 12 and 39 weeks) 5. Body Mass index (baseline and 6, 12 and 39 weeks) 6. Performance status (baseline and 6, 12 and 39 weeks) 7. Self-reported physical activity, Quality of Life (EORTC QLQ C-30) (baseline and at 6, 12 and 39 weeks) 8. General Wellbeing (SF 36) (baseline and at 6, 12 and 39 weeks) 9. Anxiety and Depression (HADs) (baseline and at 6, 12 and 39 weeks) 10. Motivational readiness (baseline and at 6, 12 and 39 weeks) 11. Decisional balance (baseline and at 6, 12 and 39 weeks) 12. Exercise self-efficacy (baseline and at 6, 12 and 39 weeks) 13. Social support, (baseline and at 6, 12 and 39 weeks) 14. Labor market affiliation - Questions on matters relating to work for people who have a cancer and consist of 13 items (baseline and at 12 and 39 weeks) 15. Cardiovascular comorbidity 16. Disease free survival and recurrence (mainly 1 and 2 year follow-up data in the following RCT)	—

Measure

Time frame

1. Dual Energy X-ray Absorptiometry / DXA scan (Baseline and 12 weeks) 2. Muscular strength (baseline and at 6, 12 and 39 weeks) 3. Blood cholesterols (baseline, 12 and 39 weeks) 4. Blood pressure, pulse (baseline and 6, 12 and 39 weeks) 5. Body Mass index (baseline and 6, 12 and 39 weeks) 6. Performance status (baseline and 6, 12 and 39 weeks) 7. Self-reported physical activity, Quality of Life (EORTC QLQ C-30) (baseline and at 6, 12 and 39 weeks) 8. General Wellbeing (SF 36) (baseline and at 6, 12 and 39 weeks) 9. Anxiety and Depression (HADs) (baseline and at 6, 12 and 39 weeks) 10. Motivational readiness (baseline and at 6, 12 and 39 weeks) 11. Decisional balance (baseline and at 6, 12 and 39 weeks) 12. Exercise self-efficacy (baseline and at 6, 12 and 39 weeks) 13. Social support, (baseline and at 6, 12 and 39 weeks) 14. Labor market affiliation - Questions on matters relating to work for people who have a cancer and consist of 13 items (baseline and at 12 and 39 weeks) 15. Cardiovascular comorbidity 16. Disease free survival and recurrence (mainly 1 and 2 year follow-up data in the following RCT)

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Countries

Denmark

Outcome results

None listed