In elderly patients over 90 years old with acute kidney injury post-infection, does prolonged intermittent renal replacement therapy improve outcomes compared to standard therapy?

Prolonged intermittent renal replacement therapy in elderly patients over 90 years old with acute kidney injury post-infection: a retrospective cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN24896690

Enrollment

Registered

2024-08-19

Start date

2019-06-01

Completion date

Unknown

Last updated

2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal replacement therapy for acute kidney injury after infection in elderly patients Urological and Genital Diseases

Interventions

Using prolonged intermittent renal replacement therapy (PIRRT), observe patient survival time and explore the correlation between clinical factors and prognosis.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients over 90 years old 2. Acute kidney injury (AKI) due to infection 3. Received Prolonged Intermittent Renal Replacement Therapy (PIRRT)

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Measured using patient records: 1.Age at baseline 2.Gender at baseline 3.Systolic Blood Pressure: Average all measurements taken from baseline over the next 3 days 4.Diastolic Blood Pressure: Average all measurements taken from baseline over the next 3 days 5.Heart Rate: Average all measurements taken from baseline over the next 3 days 6.Creatinine at baseline 7.Estimated Glomerular Filtration Rate at baseline 8.Urea at baseline 9.Sodium at baseline 10.Potassium at baseline 11.Calcium at baseline 12.Phosphorus at baseline 13.B-type Natriuretic Peptide at baseline 14.Hemoglobin at baseline 15.White Blood Cell Count at baseline 16.Neutrophil Count at baseline 17.Lymphocyte Count at baseline 18.Platelet Count at baseline 19.C-Reactive Protein at baseline 20.Procalcitonin at baseline 21.Prothrombin Time at baseline 22.Activated Partial Thromboplastin Time at baseline 23.SOFA Score at baseline 24.APACHE II Score at baseline	—

Measure

Time frame

Measured using patient records: 1.Age at baseline 2.Gender at baseline 3.Systolic Blood Pressure: Average all measurements taken from baseline over the next 3 days 4.Diastolic Blood Pressure: Average all measurements taken from baseline over the next 3 days 5.Heart Rate: Average all measurements taken from baseline over the next 3 days 6.Creatinine at baseline 7.Estimated Glomerular Filtration Rate at baseline 8.Urea at baseline 9.Sodium at baseline 10.Potassium at baseline 11.Calcium at baseline 12.Phosphorus at baseline 13.B-type Natriuretic Peptide at baseline 14.Hemoglobin at baseline 15.White Blood Cell Count at baseline 16.Neutrophil Count at baseline 17.Lymphocyte Count at baseline 18.Platelet Count at baseline 19.C-Reactive Protein at baseline 20.Procalcitonin at baseline 21.Prothrombin Time at baseline 22.Activated Partial Thromboplastin Time at baseline 23.SOFA Score at baseline 24.APACHE II Score at baseline

—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

China

Contacts

Public ContactZheng Zhang

88dahongmao88@sina.com+86 18811414199

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026