Stroke rehabilitation Nervous System Diseases Stroke
Conditions
Interventions
We wanted to investigate if a combination of aerobic exercise and training of motor skill is better than motor skill training only in rehabilitation of stroke patients. In this study we will use CIMT
Sponsors
Umeå University (Sweden)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. An approval from the patient's physician 2. Aged 18 years and over, either sex 3. First time stroke 4. Stroke =3 months ago 5. BL-motor assessment score less than or equal to 45 6. Able to pick up and release a tennis ball 3 times in 1 minute 7. Mini-mental state examination (MMSE) score greater than or equal to 24 8. Able to cycle on a stationary bicycle 4 x 5 minutes with 1 minute rest between intervals at an exertion level corresponding to 13 on Borgs RPE-scale
Exclusion criteria
Exclusion criteria: 1. Participants in both groups missing 3 hours or more of training 2. Participants in the intervention group missing more than one session of aerobic exercise, or from two or more interrupted aerobic exercise sessions lacking the same amount of aerobic exercise. 3. Other brain injury than stroke, e.g. intracranial haemorrhage caused by aneurysmal rupture or trauma 4. Neurological disorder such as Parkinson's disease or peripheral nerve damage 5. Stroke affecting brainstem and/or cerebellum 6. Previous participation in constraint-induced movement therapy (CIMT) 7. Current participation in other stroke treatment directed at motor skill 8. Injection of anti-spasticity drugs into upper extremity musculature within the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor skill by BL-motor assessment, at baseline and after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Motor skill by Twenty-five Hole Peg Test, at baseline and after intervention 2. Hand grip isometric strength by dynamometer, at baseline and after intervention 3. Cognitive ability by MMSE, at baseline and after intervention 4. Effect of CI-therapy by BL-motor assessment (BLMA), Twenty-five Hole Peg Test (THPT), hand grip isometric strength by dynamomter, at basline and after intervention 5. Effect of CI-therapy, by BLMA and THTPT, with regard to age, sex, motor skill at baseline, time since stroke and whether stroke affects dominant hand 6. The effect of the participants expectation (Likert-type scale) of the effect of CI-therapy on the effect of CI-tharapy by BLMA and THPT, at basline and after intervention 7. If motivated, in a secondary analysis of our primary outcome and secondary outcomes 1-6, we will adjust for clinic and in this analysis we will exclude clinics contributing with less than four participants 8. Concurrent validity of THPT by BLMA and Fugl-Meyer assessment 9. Test-retest reliability of THPT | — |
Countries
Sweden
Outcome results
None listed