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Nocturnal nasal postive pressure ventilation plus oxygen therapy versus oxygen alone in severe stable chronic obstructive pulmonary disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN24818612
Enrollment
Unknown
Registered
2002-10-10
Start date
2002-01-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory diseases Respiratory

Interventions

Patients will then be randomized into two groups receiving: 1. Non-invasive positive pressure ventilation (NPPV) plus LTOT, or 2. LTOT plus oral placebo over a 3-month period. NPPV will be delivered

Sponsors

Hong Kong Health Services Research Fund (Hong Kong)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with severe stable chronic obstructive pulmonary disease with hypercapnic respiratory failure already on domiciliary long-term oxygen therapy (LTOT)

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026