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Gastric Lavage in unselected acute organophosphate poisoning (OP)

Gastric Lavage in unselected acute organophosphate poisoning (OP)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN24754520
Enrollment
908
Registered
2006-01-25
Start date
2006-03-01
Completion date
Unknown
Last updated
2021-09-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Organophosphate poisoning Injury, Occupational Diseases, Poisoning Organophosphate poisoning

Interventions

Patients will receive gastric lavage on admission irrespective of whether they have had experience of it or not. Because of the ethical problem in China, we will not analyse the OP patients with no ga
the tube is then put through the nose. The tube is confirmed in the stomach by pulling out gastric content or if a sound is heard in the stomach area. The gastric content is sucked out first and then
the procedure will be done by skilled medical staff. The lavage will be stopped as soon as any serious complication happens. A 10 ml blood sample with Ethylenediamine Tetraacetic Acid

Sponsors

Peking Union Medical College Hospital (China)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients admitted to the medical wards with a history of acute organophosphate poisoning through stomach

Exclusion criteria

Exclusion criteria: 1. Under the age of 18 years 2. Known to be pregnant 3. Have ingested other kinds of poison at the same time

Design outcomes

Primary

MeasureTime frame
All-cause mortality at hospital discharge.

Secondary

MeasureTime frame
1. % of patients requiring intubation because of the respiratory failure 2. Period of ventilation 3. % of patients developing the intermediate syndrome (cranial nerve palsies and/or proximal weakness, without distal weakness, after resolution of the cholinergic crisis) 4. Number of the organ dysfunction and 50% recovery time for blood acetylcholinesterase enzyme activity

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026