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Comparison of the bioavailability of vitamin D2 and D3

Comparison of the bioavailability of vitamin D2 and vitamin D3 in healthy volunteers when consumed at different levels in a malt drink

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN24666304
Enrollment
40
Registered
2011-08-02
Start date
2011-02-22
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D supplementation Nutritional, Metabolic, Endocrine Vitamin D deficiency

Interventions

1. Participants were randomly allocated to placebo or one of 4 experimental treatments of vitamin D: 1.1. 5ug cholecalciferol or 1.2. 5ug ergocalciferol or 1.3. 10ug cholecalciferol or 1.4. 10ug erg

Sponsors

GlaxoSmithKline (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy males or females 2. Ages of 18 - 65 years

Exclusion criteria

Exclusion criteria: 1. Seated blood pressure >160/105 mm Hg 2. Body Mass Index 35 kg/m2 3. Taking vitamin and mineral supplements (including cod-liver oil), or prescription calcium/vitamin D 4. Recent exposure to high UVB light (since 1 December 2010) 5. Intolerance to study product (lactose, milk protein) 6. Chronic renal, liver or inflammatory bowel disease 7. Diabetes 8. Unwilling to follow the protocol and/or give informed consent 9. Unwilling to restrict consumption of oily fish to no more than 2 portions of oily fish per week

Design outcomes

Primary

MeasureTime frame
Change in serum 25(OH)D concentrations

Secondary

MeasureTime frame
Change in calcium and parathyroid hormone concentrations

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026