Optimising blood-circulation and oxygen delivery in planned abdominal aortic surgery

Optimising stroke volume and oxygen delivery in elective abdominal aortic surgery: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN24645910

Enrollment

Registered

2010-09-03

Start date

2008-06-01

Completion date

Unknown

Last updated

2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective abdominal aortic surgery

Interventions

Patients were assigned to Individual Goal Directed Therapy (IGDT) or control groups by computer-generated random sequence. The intervention period started preoperatively, when monitoring with the Li

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consecutive patients admitted for elective abdominal aortic surgery

Exclusion criteria

Exclusion criteria: 1. Chronic renal end-failure 2. Preoperative Lithium therapy 3. Body weight < 40 Kg (88,18 lbs)

Design outcomes

Primary

Measure	Time frame
One or more severe postoperative complications: 1. Septic shock 2. Pneumonia 3. Superficial wound infection 4. Deep wound infection 5. Abdominal infection 6. Urinary tract infection 7. Pulmonary embolus 8. Acute Respiratory Distress Syndrome (ARDS) 9. Cardiac arrest 10. Acute coronary syndrome 11. Cardiac arrhythmia (acute treatment needed) 12. Pulmonary oedema 13. Deep venous thrombosis 14. Cerebral thrombosis 15. Cerebral haemorrhage 16. Lower limb paresis 17. Acute kidney insufficiency 18. Intraabdominal hypertension 19. Severe upper gastrointestinal bleeding 20. Gastrointestinal paralysis 21. Creatine Kinase (CK) > 5000 22. Reoperation 23. Readmission to ICU 24. Need of respirator 25. Need of hemodialysis 26. Dead	—

Measure

Time frame

One or more severe postoperative complications: 1. Septic shock 2. Pneumonia 3. Superficial wound infection 4. Deep wound infection 5. Abdominal infection 6. Urinary tract infection 7. Pulmonary embolus 8. Acute Respiratory Distress Syndrome (ARDS) 9. Cardiac arrest 10. Acute coronary syndrome 11. Cardiac arrhythmia (acute treatment needed) 12. Pulmonary oedema 13. Deep venous thrombosis 14. Cerebral thrombosis 15. Cerebral haemorrhage 16. Lower limb paresis 17. Acute kidney insufficiency 18. Intraabdominal hypertension 19. Severe upper gastrointestinal bleeding 20. Gastrointestinal paralysis 21. Creatine Kinase (CK) > 5000 22. Reoperation 23. Readmission to ICU 24. Need of respirator 25. Need of hemodialysis 26. Dead

—

Secondary

Measure	Time frame
1. Flow-related haemodynamic parameters (SVI and Do2I) measured by the LiDCO-plus-system (LiDCO Ltd., Cambridge, UK) 2. Length of stay in Intensive Care Unit 3. Length of hospital stay	—

Countries

Denmark

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026