Infertility Urological and Genital Diseases Female infertility
Conditions
Interventions
Endometrium scratching in seventh day after observation of Luteinizing hormone (LH) surge prior to an IVF or frozen embryo transfer (FET) cycle in study group. No extra administration prior to an IVF
Sponsors
Zhejiang University (China)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients with repeated implantation failure (two or more) undergoing in vitro fertilization embryo transfer (IVF-ET) or frozen embryo transfer (FET) 2. Patients aged no more than 40 years old 3. Patients with basal follicle-stimulating hormone (FSH)<10IU/L 4. Patients without history of uterine cavity operation in two months
Exclusion criteria
Exclusion criteria: 1. Patients with hydrosalpinx 2. Patients with polycystic ovary syndrome (PCOS) 3. Patients with history of endometrium adhesion 4. Patients with uterine malformation; uterine fibroid 5. Patients with acute genital tract inflammation 6. Patients with history of using hormone such as oral contraceptive in one month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Implantation rate 2. Clinical pregnancy rate defined as the presence of a fetal sac by ultrasound scanning | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Endometrial thickness 2. Endometrial type | — |
Countries
China
Outcome results
None listed