Randomised controlled trial of injection of botulinum toxin into the internal anal sphincter versus control in treatment of chronic idiopathic constipation in children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN24521269

Enrollment

Registered

2005-09-30

Start date

2003-10-08

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System: Constipation Digestive System Constipation

Interventions

A randomized-controlled trial of botulinum toxin injection versus control in children with chronic idiopathic constipation. The children are randomly allocated by surgeons into two treatment groups af

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 80 children with idiopathic chronic constipation referred for anorectal manometry and inpatient bowel management programme.

Exclusion criteria

Exclusion criteria: 1. Patients younger than 3 years old or older than 16 years 2. Severe learning difficulty 3. Evidence of Hirschsprungs disease on anorectal manometry 4. Previous anal surgery

Design outcomes

Primary

Measure	Time frame
Improvement in patients symptom severity score determined by parents completed questionnaire.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026