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Different approaches to partner notification in primary care

The relative clinical and cost-effectiveness of three contrasting approaches to partner notification for curable sexually transmitted infections (STIs): a cluster randomised trial in primary care

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN24160819
Enrollment
3300
Registered
2010-03-18
Start date
2010-05-01
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexually transmitted infections (STIs) Infections and Infestations Unspecified sexually transmitted disease

Interventions

We will compare three different interventions in partner treatment: 1. Patient referral: patients are given information about their infection, and asked to tell their partner about the problem and t

Sponsors

University of Sussex (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Practices: 1. Practices from the MRC General Practice Research Framework (GPRF), the South East Primary Care Research Network (PCRN-SE) or the Primary Care Research Network Greater London (PCRN-GL) 2. Registered populations of 5000 or more 3. A maximum of six practices considering themselves as "student health centres" will be recruited, and no more than four regarding themselves as running "locally enhanced services for sexual health" Individuals: 1. Belonging to the target population above 2. Over the age of 16 years (either sex) at the time of first attendance for this problem, or of screening for chlamydia (NB patients will be eligible if they refuse to communicate with partners, given the objectives of the study)

Exclusion criteria

Exclusion criteria: Patients: 1. Learning difficulties 2. Unable to read trial materials after discussion with clinical staff 3. No means of communication acceptable to the patient for him/herself

Design outcomes

Primary

MeasureTime frame
1. Number of main partners per index patient treated for chlamydia and/or gonorrhoea/nonspecific urethritis/pelvic inflammatory disease 2. Proportion of index patients testing negative for the relevant STI at 3 months

Secondary

MeasureTime frame
1. Number of partners per index patient presenting for treatment 2. Proportion of index patients having at least one partner treated 3. Number of main, casual and ex-partners per index patient tested for the relevant STI 4. Number of main, casual and ex-partners testing positive for the relevant STI 5. Number of index patients tested for HIV by 3 months 6. Number of current partners tested for HIV by 3 months 7. Time to definitive treatment of index patient for the relevant STI 8. Time to definitive treatment of current partner for the relevant STI 9. Uptake by index patients of "contract" and "provider" referral for one or more partners, within the relevant randomised groups 10. Patient-related factors impacting on partner notification or STI disclosure to main, casual and ex-partners An important secondary aim is to identify what patient-related or psychological factors impact on disclosure.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 18, 2026