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Can a device that stimulates cell activity using radio electric emissions improve recovery from traumatic joint injuries?

Neurobiological modulation using the Radio Electric Asymmetric Conveyer (REAC) to improve recovery in acute post-trauma joint injuries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN24138677
Enrollment
50
Registered
2019-09-30
Start date
2019-04-29
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic knee medial collateral ligament lesion Musculoskeletal Diseases

Interventions

50 outpatients with acute post-traumatic knee medial collateral ligament lesion in care at Health Sciences Department of the Federal University of Amapá, Macapá – Brazil were enrolled for this single-

Sponsors

Federal University of Amapá
Lead Sponsor
Rinaldi Fontani Institute and Foundation
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years 2. Diagnosed using MRI or ultrasound with a grade 3 or 2 injury to the medial collateral ligament of the knee 3. Diagnosed no more than 4 days before the day of enrolment in the study

Exclusion criteria

Exclusion criteria: Previous other joint disorders of the affected knee

Design outcomes

Primary

MeasureTime frame
Time to healing, with healing assessed using the following assessments by the medical practitioner and subjective assessments of the patient at the first clinical examination, within 4 days after the trauma/accident (T0); immediately after the administration of the Neuro Postural Optimization (NPO) treatment, which is the one-session treatment delivered on the subject’s ear (T1); at the end of the 18th session of Tissue Optimization (TO) treatment (T2); at the 30 day-follow up (T3): Medical assessments: 1. Functional dysmetria. The evaluation of dysmetria is an evaluation of neurological semiology aimed at observing the presence of a dysfunction. Evaluation of dysmetria in the lower limbs can be evidenced, by lightly and symmetrically placing the operator's hands on the femoral quadriceps of the subject being examined in supine position, taking care that the nails of the two left and right thumbs are perfectly aligned. Asking the subject to move from the supine to the sitting position, a progressive misalignment of the two thumbs is highlighted. This manoeuvre allows the operator to perceive and highlight the asymmetric activation of symmetrical muscle groups (dysmetria), such as the quadriceps muscles. In this study, we observed the presence or absence of the phenomenon before (T0) and after NPO treatment (T1). 2. Joint swelling assessment using the scale none (1), little (2), very (3), very much (4) 3. Perception of pain caused during orthopaedic assessment manoeuvres assessed using the scale none (1), little (2), very (3), very much (4) 4. Assessment of patellar ballottement. The procedure to assess patellar ballottement requires that the patient be placed in the supine position with leg straight. The examiner applies anterior to posterior pressure over the patella, and gently oscillates the patella, palpating for motion. Increased motion or spongy joint feel means intra-articular kne

Secondary

MeasureTime frame
Pain reduction in post-traumatic second and third-degree lesions of the medial collateral ligament of the knee evaluated with verbal analogue scale none (1), little (2), very (3), very much (4) at the first clinical examination, within 4 days after the trauma/accident (T0); immediately after the administration of the Neuro Postural Optimization (NPO) treatment, which is the one-session treatment delivered on the subject’s ear (T1); at the end of the 18th session of Tissue Optimization (TO) treatment (T2) and at the 30 day-follow up (T3)

Countries

Brazil, Italy

Contacts

Public ContactAna Rita Pinheiro Barcessat
ritabarcessat@gmail.com9681334223

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026