Post-op oesophageal Doppler trial: effect on clinical outcome of extension of oesophageal Doppler goal-directed fluid optimisation into the post-operative recovery period

Effect on clinical outcome of extension of oesophageal Doppler goal-directed fluid optimisation into the post-operative recovery period: a randomised control trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN24020298

Enrollment

Registered

2012-09-14

Start date

2011-05-24

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improving perioperative care for elective colorectal surgery within an Enhanced Recovery Programme Digestive System

Interventions

Intervention group will have 16 hours post-operative oesophageal Doppler cardiac output monitoring with nurse-led stroke volume optimisation in an overnight intensive recovery (OIR) unit. Control gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Consecutive elective or semi-elective patients due to undergo colorectal surgery as part of Enhanced Recovery Protocol involving resection or anastamosis of bowel 2. High-risk participants will be defined as having (1) pre-operative ASA grade III+ OR anaerobic threshold <11 ml/min/kg on cardiopulmonary exercise testing OR undergoing major complex surgery (as per OPCS 4.5 classification - Office of Population, Censuses and Surveys Classification of Surgical Operations and Procedures) 3. Ages 18 and over (no upper limit)

Exclusion criteria

Exclusion criteria: 1. Emergency surgery 2. Lack of capacity to consent 3. Pregnancy 4. Contraindications to oesophageal Doppler probe: 4.1. Nasal injuries or polyps 4.2. Severe oesophageal/laryngeal/pharyngeal disease 4.3. Recent oesophageal/laryngeal/pharyngeal surgery 4.4. Thoracic aortic aneurysm 4.5. Severe bleeding diathesis 4.6. Long-term systemic steroid therapy 4.7. Portal hypertension All excluded patients from patient groups to be reported in results

Design outcomes

Primary

Measure	Time frame
Post-operative length of stay (in days)	—

Secondary

Measure	Time frame
1. Oxygen delivery index at end of 16h post-operative recovery period 2. Mean oxygen delivery index over 16h post-operative recovery period 3. Morbidity 4. Functional recovery (mobility and return of gastrointestinal function) 5. In-hospital and 30-day mortality	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026