Detrusor hypoactivity (underactive bladder) Urological and Genital Diseases
Conditions
Interventions
Patients will be selected in the urology service of the University Hospital with a diagnosis of detrusor hypoactivity. 10 patients will be selected and invited to sign the informed consent form. These
Sponsors
Federal University of Mato Grosso do Sul
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female patients with a urodynamic study showing only detrusor hypocontractility, without the presence of an obstructive factor to urinary flow 2. On a clean intermittent catheterization regime 3. Not undergoing any surgical procedure in the lower urinary tract in the last 12 months
Exclusion criteria
Exclusion criteria: 1. End-stage renal failure (with oligo-anuria) 2. Recurrent urinary tract infection 3. Non-adherence to clinical monitoring protocols and clean intermittent auto-catheterization 4. Presence of any malignant neoplasm confirmed in treatment or recently treated or even any suspicion of cancer will be an important exclusion criterion due to contraindication to the use of stem cells in these patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bladder function will be assessed through urodynamic study before the patient is subjected to fat collection and 60 days after the second stem cell transplant | — |
Secondary
| Measure | Time frame |
|---|---|
| The quality of life of patients with urinary incontinence secondary to this voiding dysfunction, assessed using the international continence on incontinence questionnaire – short form (ICIQ-SF) before and 60 days after the second stem cell transplant | — |
Countries
Brazil
Contacts
Public ContactHenrique Coelho
Outcome results
None listed