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A small randomised controlled trial on ST-MBCT + TAU versus COMET + TAU for patients with a personality disorder

A small randomised controlled trial on ST-MBCT + TAU versus COMET + TAU for patients with a personality disorder: effectiveness, predictors and mediators of outcome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN23894653
Enrollment
60
Registered
2017-09-13
Start date
2012-03-01
Completion date
Unknown
Last updated
2019-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Outpatients with personality disorder(s) Mental and Behavioural Disorders

Interventions

session four: mindfulness to schema coping
session two: more mindfulness for the environment
session five: mindful allowing and accepting what is
session three: mindfulness for respiration and painful memories
For this pilot study, a parallel-groups randomized single-blind trial was used. Randomization to the condition SMT or COMET was performed by GraphPad software (http://www.graphpad.com/quickcalcs/rando
Bohnen, de Winter & Hoenkamp, 2011) and the Structured Clinical Interview of DSM-IV Disorders II (SCID-II, First, Spitzer, Gibbon, Williams, & Benjamin, 1997
Weertman, Arntz, & Kerkhofs, 2000). After inclusion, the patients filled in five self-report questionnaires before the start of the group training, directly after the last session of the group trainin
session six: mindfulness to schemas facts or fiction
session seven: mindful taking care of yourself by the Healthy adult and the Happy child (Young et al., 2011)
session eight: schema mindfulness and the future. COMET A negative self-image is a problem common to many psychiatric disorders (Appelo & Korrelboom, 2005) and to vari

Sponsors

GGZ Delfland
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients (male or female) with a main diagnosis on Axis II, meaning one or more cluster A, B, C personality disorders or a personality disorder NOS 2. Aged 18 to 65 years 3. Patients were allowed to have a diagnosis on Axis I other than the exclusion criteria

Exclusion criteria

Exclusion criteria: 1. Acute psychosis 2. Addiction of such severity that clinical detoxification was indicated 3. Severe suicidality for which hospitalisation was necessary 4. Untreated ADHD, bipolar I disorder and an IQ lower than 80 5. Patients were not allowed to have had Schema therapy or COMET in the past 12 months

Design outcomes

Primary

MeasureTime frame
General psychological distress assessed using the Symptom Checklist-90 (SCL-90; Dutch version by Arrindell & Ettema, 1986). The SCL-90 is a 90-item self-report questionnaire which measures the following complaints: Agoraphobia, Anxiety, Depression, Somatic complaints, Insufficiency of thinking and doing, Interpersonal sensitivity, Hostility, Sleeping problems. The sum score represents a Global Severity Index. The Dutch version is reliable (Cronbach’s alpha 0.97 by total score) and valid (Arrindell & Ettema, 1986). In this study the Cronbach’s alpha for the total score was 0.88. We used the Global severity index (GSI) as primary outcome. Method of measurement: Questionnaire (self-assessment) Timepoints: T1: Before the start of the therapy T2: Directly after the last therapy session T3: One month after T2

Secondary

MeasureTime frame
1. Mindfulness assessed with the Mindfulness Attention Awareness Scale (MAAS, Brown & Ryan, 2003; Dutch version by Schroevers, Nyklícek, & Topman, 2008). The MAAS is a 15-item self-report questionnaire which represents the frequency of everyday mindfulness experiences. Previous studies found a one-factor structure. Cronbach’s alpha ranged between .82 - .87 (Carlson & Brown, 2005; Brown & Ryan, 2003). The Dutch version is reliable (Cronbach’s alpha 0.81) and valid (Schroevers, Nyklícek, & Topman, 2008). In this study the Cronbach’s alpha was 0.86. This study used the sum score of the MAAS as an index of mindfulness 2. Self-esteem assessed using the Rosenberg Self-Esteem Scale (RSES, Rosenberg, 1965; Dutch version by Franck, de Raedt, Barbez, & Rosseel, 2008). The RSES is a 10-item self-report questionnaire assessing the degree of self-esteem. The Dutch version of the RSES is reliable (Cronbach’s alpha 0.86) and valid (Franck, de Raedt, Barbez, & Rosseel, 2008). The Cronbach’s alpha in this study was 0.87. This study used the sum score of RSES as a measure of self-esteem. 3. Schemas assessed with the Young Schema Questionnaire, (YSQ; Young & Brown, 1994; Dutch version by Rijkeboer, 2005). The YSQ is a 205-item self-report questionnaire which represents sixteen dysfunctional schema’s: Abandonment/ Instability, Mistrust/Abuse, Emotional Deprivation and Social Isolation/Alienation (schema domain 1: Disconnection and Rejection); Dependence/Incompetence, Enmeshment/ Undeveloped Self and Failure (schema domain 2: Impaired Autonomy and Performance); Entitlement/ Grandiosity and Insufficient Self-control/Self-discipline (schema domain 3: Impaired Limits); Subjugation and Selfsacrifice/ Approval Seeking/Recognition Seeking (schema domain 4: Other Directedness); and Emotional Inhibition and Unrelenting Standards/Hypercriticalness (schema domain 5: Overvigilance and Inhibition). The Dutch version of the YSQ is reliable (Cronbach’s alpha ranging

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026