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Comparative insect repellency study of combined lemongrass and peppermint oil lotion versus 25% DEET lotion against mosquitoes

Comparative study of the insect repellency action of combined lemongrass oil and peppermint oil lotion versus 25% DEET (N,N-diethyl-meta-toluamide) lotion against female Aedes aegypti mosquitoes

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN23577135
Enrollment
46
Registered
2024-02-09
Start date
2022-04-21
Completion date
Unknown
Last updated
2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dengue Infections and Infestations Dengue

Interventions

Participants were randomized by simple randomization to one of two treatment groups. 5 grams of Repellent A - Combined Lemongrass and Peppermint oil lotion and 5 grams of Positive Control Repellent B

Sponsors

Research Institute for Tropical Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthy male or female aged 18–40 years 2. Must know how to read and write 3. Must be willing to comply with the study protocol requirements 4. Must be willing to sign an informed consent after having clearly understood its content 5. Must be willing to have photos taken for documentation purposes during the experiment

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women 2. Those with a history of allergy or hypersensitivity reactions to insect repellents and its components 3. Those with a history of adverse reactions to insect bite 4. Those who have active skin lesions or other dermatological disorders (like atopic dermatitis, psoriasis) 5. Those with a history of other comorbid conditions (diabetes, hypertension, malignancy) 6. Current or ex-smoker (=10 pack years)

Design outcomes

Primary

MeasureTime frame
The % protection over time was determined by counting the number of mosquitoes landing/probing on the treated arm (T) in relation to the number of landings on the control untreated arm (C) of the same individual (% p = ((C-T)/C)) x 100) for a 3-minute exposure every hour (1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours).

Secondary

MeasureTime frame
Complete protection time was calculated as the number of minutes elapsed between the time of repellent application and the first mosquito landing or probing for a 3-minute exposure every hour (1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours).

Countries

Philippines

Contacts

Public ContactAira Monica Abella
aika2122001@gmail.com+63 (0)9175714806

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026