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The CHICO (Children with Cough) trial

A feasibility randomised controlled trial investigating the clinical and cost effectiveness of a complex intervention to improve the management of children presenting to primary care with acute respiratory tract infection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN23547970
Enrollment
500
Registered
2014-06-27
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Children, Primary Care

Interventions

30 practices are recruited with 10 in reserve. Randomisation at the practice level as it is a cluster RCT. 15 practices will be randomised to each arm initially and the 10 reserves may be randomised d
Study Entry: Multiple Randomisations

Sponsors

University of Bristol (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Clinicians: GPs and prescribing nurses are eligible to recruit children to the study GP practices will be included if they have at least Internet Explorer version 8 on their IT systems Children can be included into the study if they meet the following criteria: 1. Children aged =3 months and <12 years 2. Presenting with an acute RTI with cough for =28 days as a main symptom (including exacerbation of asthma) 3. Presenting with illnesses such as RTI and epilepsy or diabetes, including infective exacerbation of asthma (non-infective exacerbation of asthma is an exclusion criterion) Target Gender: Male & Female; Upper Age Limit 11 years ; Lower Age Limit 3 months

Exclusion criteria

Exclusion criteria: Children will not be eligible for the study if: 1. They are aged 28 days 6. They are at greater risk of serious infection; they have chronic diseases/multi-morbidities that increase the risk of RTI complications

Design outcomes

Primary

MeasureTime frame
Feasiblity; Timepoint(s): September 2014-September 2015

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 8, 2026