Prevention of side branch stent under-expansion during double stent crush percutaneous intervention procedure to treat coronary artery bifurcation lesions Circulatory System
Conditions
Interventions
10 patients presenting with severe bifurcation stenosis of the LAD-D eligible for two stenting DK Crush procedures, five with proximal side optimization (PSO) modification (control arm), and five DK C
Sponsors
Jilin Heart Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 18 to 75 years old 2. Left anterior descending artery – diagonal branch bifurcation (LAD-D) Medina 1.1.1, with long (>10 mm) and severe stenoses (>75%) of the long (>75 mm) side branch (SB) 3. Undergoing two stent bifurcation PCI with Crush technique
Exclusion criteria
Exclusion criteria: 1. Patients less than 18 years old 2. Cardiogenic shock 3. Renal failure 4. Recent major bleeding 5. Allergy to aspirin or clopidogrel 6. On anticoagulant therapy 7. No suitable anatomy for OCT (extreme tortuosity, very small vessels<2.25 mm in diameter)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Stent areas in the ostial segment of the side branch and protruding DES areas in the main branch before the side branch stent is crushed, measured with optical coherence tomography (OCT) during the index procedure, after side branch stent implantation 2. Space of optimal wiring (SOW) measured with OCT after crush | — |
Secondary
| Measure | Time frame |
|---|---|
| Gaps in the scaffolding within the ostial segment of the SB DES measured with OCT at the end of the PCI procedure | — |
Countries
China
Outcome results
None listed