Adenovirus conjunctivitis Eye Diseases
Conditions
Interventions
The trial investigated whether a single-dose application of povidone-iodine could shorten recovery time in adenoviral conjunctivitis.
Intervention arm: Single application of 5% povidone-iodine ophtha
supportive treatment continued for 7–10 days as required.
Follow-up: Clinical reviews on Day 3, Day 7, Day 10, and Day 14 (resolution of conjunctival hyperaemia, discharge, and follicular reaction).
Sponsors
Al Karkh General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged over 14 years 2. Presented within 3 days of symptoms and signs of ocular infection which included: redness, pain, lid swelling, mucopurulent discharge, lymphadenopathy and follicular reaction
Exclusion criteria
Exclusion criteria: 1. Age under 14 years 2. Onset of symptoms more than 3 days before presentation 3. Any ocular treatment received before presentation 4. Patients with existing ocular diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to clinical recovery from adenoviral conjunctivitis (days), measured from day of intervention until complete resolution of conjunctival congestion, tearing and discharge, assessed by slit-lamp examination and patient-reported symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change in symptom severity score (redness, tearing, foreign body sensation, discharge) measured using a standardized clinical grading scale at baseline, day 3, day 7, and day 14 2. Rate of symptom improvement (% of patients showing =50% reduction in symptoms by day 7) 3. Incidence of adverse events (ocular irritation, allergy, keratitis, or other complications) during the follow-up period | — |
Countries
Iraq
Contacts
Public ContactRawan Altraqchi
Outcome results
None listed