Comparison of the effects of sevoflourane and ketamine on intraocular pressure (IOP) in healthy patients and patients with glaucoma

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN22914223

Enrollment

Registered

2005-11-16

Start date

2005-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma Eye Diseases Glaucoma

Interventions

Intraocular pressure measurements will be recorded in patients with glaucoma and in healthy patients. Both sevoflourane and ketamine are commonly used anaesthetic agents. Patients will be randomised

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients unwilling/unable to give informed consent 2. Patients with irregular corneas or other ocular abnormalities not allowing for an adequate IOP measurement

Design outcomes

Primary

Measure	Time frame
Change in intraocular pressure after administration of anesthetic agent: 1. How greatly does the IOP change? 2. What percentage of patients in each group have a statistically significant change?	—

Secondary

Measure	Time frame
Effect of pulse, blood pressure, oxygenation, baseline IOP, baseline eye disease on intraocular pressure.	—

Countries

United States of America

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026