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Ambulatory oxygen improves the effectiveness of pulmonary rehabilitation in selected patients

The effectiveness of ambulatory oxygen versus room air during pulmonary rehabilitation in patients who are hypoxaemic on exertion and respond to supplemental oxygen at baseline

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN22894945
Enrollment
52
Registered
2010-05-13
Start date
2007-09-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic respiratory disease Respiratory Chronic respiratory disease

Interventions

Patients randomised into two groups: 1. Ambulatory oxygen group exercise within pulmonary rehabilitation and at home using ambulatory oxygen 2. Room air group exercise within pulmonary rehabilitation

Sponsors

Surrey Community Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients (aged 50 - 87 years, either sex) with chronic respiratory disease enrolled in pulmonary rehabilitation who have resting saturations greater than 92%, but desaturate by greater than 4% and to less than 90% on exertion and who then walk greater than 10% further with ambulatory oxygen during field exercise testing at baseline.

Exclusion criteria

Exclusion criteria: 1. Already on oxygen therapy (long-term or ambulatory) 2. Those who do not desaturate significantly on exertion 3. Those who do desaturate but do not demonstrate benefit using ambulatory oxygen at baseline

Design outcomes

Primary

MeasureTime frame
Exercise tolerance measured using the Endurance Shuttle Walk Test pre- and post-pulmonary rehabilitation

Secondary

MeasureTime frame
1. Quality of life measured using the Self-Report Chronic Respiratory Questionnaire 2. Anxiety and depression measured using the Hospital Anxiety and Depression Scale 3. Function measured using the Surrey Information on Function Tool All are questionnaires completed pre- and post-pulmonary rehabilitation.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026