Critically ill patients with respiratory failure of different etiologies and prolonged mechanical ventilation requirements Respiratory
Conditions
Interventions
The tracheotomy was performed in accepted patients according to the result of randomization: early (before day 8) or late (from day 14 onwards of MV). In the remaining patients the decision of whether
Sponsors
University Hospital of Bellvitge (Hospital Universitari de Bellvitge) (Spain)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients admitted to the intensive care unit (ICU) with: 1. Aged over 17 2. Over 2 days of mechanical ventilation and expected by attending physician to be 7 or more days of mechanical ventilation
Exclusion criteria
Exclusion criteria: 1. Patients already tracheotomized 2. Patients previously included in another trial 3. Technical difficulty to perform a percutaneous tracheotomy 4. Patients without limitation of life support but any of the following conditions: intracranial hypertension (ICP> 15), risk of bleeding (platelets 1.5), severe respiratory failure (PEEP> 10cmH20 or PO2 / FiO2 <100) 5. Patients with poor prognosis and any type of decision to limit life support measures 6. Patients requiring urgent tracheotomy on medical grounds (to improve the management of the upper airway, neurological illness, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality at 90 days of ICU admission | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of days free of mechanical ventilation at 28 and 90 days 2. ICU length of stay 3. Number of days with continuous perfusion of sedatives 4. Incidence of pneumonia These outcomes are measured using patient records. | — |
Countries
Spain
Outcome results
None listed