Prospective controlled randomised trial on Prevention Of Postoperative abdominal Adhesions by icodextrin 4% solution after laparotomic operation for small bowel obstruction caused by adherences

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN22061989

Enrollment

180

Registered

2007-07-05

Start date

2007-01-01

Completion date

Unknown

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of postoperative abdominal adhesions Surgery Abdominal adhesions

Interventions

The study will be performed in the Department of Transplant, General and Emergency Surgery of St Orsola-Malpighi University Hospital (Bologna, Italy)

a large teaching institution, with the participation of all surgeons who accept to be involved, together with the Emergency Surgery Department of Maggiore Hospital (Bologna, Italy). These two institut

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients (over 18 years) 2. Submitted to laparotomic surgical procedures for ASIO 3. Clinical and radiological evidence of adhesive small intestine obstruction 4. American Society of Anesthesiologists (ASA) grade one to three patients 5. Informed consent

Exclusion criteria

Exclusion criteria: 1. Intra-abdominal cancer 2. Peritoneal contamination 3. Inflammatory Bowel Disease (IBD) 4. Positive history of radiotherapy 5. Patients with an intra-operative findings of different pathology will be excluded from the study

Design outcomes

Primary

Measure	Time frame
To evaluate the therapeutic role of icodextrin 4% to reduce ASIO incidence.	—

Secondary

Measure	Time frame
To reduce adherences rate (in case of reoperation for ASIO).	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 4, 2026