Domain of adult obesity Nutritional, Metabolic, Endocrine
Conditions
Interventions
1. Anthropometrics (body measurements)
2. Biological parameters and microvascular function (e.g. blood pressure, pulse rate)
Sponsors
Sousse University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adults with BMI = 30kg/m²
Exclusion criteria
Exclusion criteria: 1. History of hypertension, antihypertensive medication or elevated sitting blood pressure (systolic blood pressure (SBP) = 140 mmHg and/or diastolic blood pressure (DBP) = 90 mmHg) 2. History of diabetes mellitus or fasting glucose > 7mmol/L 3. Any history or finding of cardiovascular disease, and/or undergone any cardiovascular procedures 4. Hyperlipidemia (total cholesterol > 6,7 mmol/L and/or triglycerides levels > 4,5 mmol/L) 5. Smoking 6. Consumption of any vasoactive medications or antioxidant supplements within the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Microvascular assessment of cutaneous blood flow performed by the laser Doppler flowmetry technique at diagnosis and after exercise training 2. Plasma microparticules quantification and characterization by Flow cytometry at diagnosis and after exercise training | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Circulating microparticles level 2. Informed written consent before inclusion | — |
Countries
Tunisia
Outcome results
None listed