The effect of a one hour bout of games-based activity on adolescent cardiovascular health

Inflammatory, glycaemic and insulinaemic response to an acute bout of high intensity, intermittent games-based activity in adolescents

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN21855728

Enrollment

Registered

2017-09-08

Start date

2015-09-01

Completion date

Unknown

Last updated

2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardio-metabolic health Circulatory System Cardio-metabolic health

Interventions

The intervention assesses the effect of an acute bout of 60-min of games-based activity (basketball) on the inflammatory, glycaemic and insulinaemic responses in adolescents when compared against a ra

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Male and female participants 2. Aged 10-12 years 3. Healthy and free of non-communicable diseases.

Exclusion criteria

Exclusion criteria: Non-communicable diseases that may alter rested inflammatory cytokines.

Design outcomes

Primary

Measure	Time frame
Inflammatory cytokines are measured acutely using a flow cytometer (Beckman Coulter Gallios™) specific multiplex bead assay (AimPlex™ multiplex assay, YSL Bioprocess Development Company, Pomona, USA) at baseline, immediately, 1 h, 2h and 3 h post-exercise. A final measurement was taken the following morning 24 h post-exercise to assess inflammatory mediators.	—

Secondary

Measure	Time frame
1. Blood glucose concentration is measured using a commercially available assay (GOD/PAP method, GL364, Randox, Ireland) at baseline, immediately and 1 h post-exercise (30 min following this participants consumed of a standardised lunch), then 30 min, 60 min and 120 min post lunch. A final blood sample was taken the following morning 24 h post-exercise to assess blood glucose. 2. Plasma insulin is measured using a commercially available ELISA (Mercodia Ltd, Sweden) at baseline, immediately and 1 h post-exercise (30 min following this participants consumed of a standardised lunch), then 30 min, 60 min and 120 min post lunch. A final blood sample was taken the following morning 24 h post-exercise to assess plasma insulin.	—

Measure

Time frame

1. Blood glucose concentration is measured using a commercially available assay (GOD/PAP method, GL364, Randox, Ireland) at baseline, immediately and 1 h post-exercise (30 min following this participants consumed of a standardised lunch), then 30 min, 60 min and 120 min post lunch. A final blood sample was taken the following morning 24 h post-exercise to assess blood glucose. 2. Plasma insulin is measured using a commercially available ELISA (Mercodia Ltd, Sweden) at baseline, immediately and 1 h post-exercise (30 min following this participants consumed of a standardised lunch), then 30 min, 60 min and 120 min post lunch. A final blood sample was taken the following morning 24 h post-exercise to assess plasma insulin.

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Countries

United Kingdom

Contacts

Public ContactKarah Dring

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026