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Coping with Unusual ExperienceS for 12-18 (CUES+)

Coping with Unusual ExperienceS for 12-18 year olds (CUES+): A transdiagnostic randomised controlled trial of the effectiveness of cognitive therapy in reducing distress associated with unusual experiences in adolescent mental health services

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN21802136
Enrollment
120
Registered
2015-01-12
Start date
2015-01-13
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Distressing unusual experiences (UEDs) in adolescents presenting to community Child and Adolescent Mental Health Services (CAMHS). Mental and Behavioural Disorders

Interventions

Therapy will comprise up to 16 sessions, delivered over 16 weeks, including individual CBTp adapted for adolescents and 3-4 family support sessions. This is crucial when working with young people and

Sponsors

King's College London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Presenting to local CAMHS 2. Current UED 3. Aged 12-18 years 4. Available for the study duration 5. Sufficient English language ability to be able to complete assessment measures and therapy (with interpreter support if necessary)

Exclusion criteria

Exclusion criteria: 1. Learning disability (IQ<70) 2. UED secondary to known neurological condition (e.g. epilepsy or brain injury) or limited to states of acute intoxication/withdrawal in the context of substance misuse

Design outcomes

Primary

MeasureTime frame
Distress at 16 weeks, assessed using the Emotional Problems subscale of the child reported version of the Strengths and Difficulties Questionnaire (SDQ). The SDQ is well-validated and routinely used in local services for youth up to 19 years.

Secondary

MeasureTime frame
Child-reported UED severity at 16 weeks, adverse events including A&E attendance and incidents of self harm, and economic costs, including QALYs. We will also measure the cognitive, social, emotional and behavioural therapy targets hypothesised to maintain UEDs, and sessional measures of therapy progress.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 8, 2026