An inconspicuous, non-invasive, mobile sensor device for real-time control of assistive technologies through facial expression

Ambulatory measurement of facial expressions in health and disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN21782066

Enrollment

150

Registered

2018-11-20

Start date

2018-11-21

Completion date

Unknown

Last updated

2022-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease, facial palsy Nervous System Diseases Parkinson's disease

Interventions

The study is divided into two parts. Part one will include 50 participants with Parkinson's disease, 50 participants with facial palsy and 50 healthy control participants. Participant

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All participants: 1. Aged 18-75 years 2. ASA I (normal, healthy) or II (mild systemic disease, no functional limitation, e.g. smoker with well-controlled hypertension) 3. Ability to read and understand English 4. Use of both hands 5. Ambulatory (able to walk around own home (walking aids are allowed)) Additional inclusion criteria for participants with facial palsy: 1. Unilateral facial palsy (i.e. one side effected) 2. A facial grading score, using the House-Brackmann scale, of less than 6 3. A facial grading score, using the Sunnybrook Facial Grading System, of less than 100 Additional inclusion criteria for participants with Parkinson's disease: 1. Clinical diagnosis of Parkinson’s disease 2. Stable medication for at least 6 weeks

Exclusion criteria

Exclusion criteria: All participants: 1. Evidence of neuro-muscular dysfunction Additional exclusion criteria for participants with facial palsy: 1. History of facial surgery (except eye lid surgery) Additional exclusion criteria for participants with Parkinson's disease: 1. Unable to walk

Design outcomes

Primary

Measure	Time frame
The range of facial expressions in response to emotional stimuli, as measured by facial muscle activity by EMG and FRAME sensors in a single visit	—

Secondary

Measure	Time frame
Measured at baseline, upon study completion, and at three-daily intervals, prompted by automated calls to their smartphone, for each day the participants are wearing FRAME: 1. Personality, assessed using OCEAN 2. Presence of any existing mental health issues, assessed using CORE-10. Participants who reveal potential mental health issues will be advised that we will write to their GP informing them of the results of the questionnaire 3. Quality of life, assessed using SF36 4. Current mood at time of assessment, assessed using Self-Assessment Mannikin (SAM) 5. Disease-specific issues, assessed using UPDRS & SAQ	—

Measure

Time frame

Measured at baseline, upon study completion, and at three-daily intervals, prompted by automated calls to their smartphone, for each day the participants are wearing FRAME: 1. Personality, assessed using OCEAN 2. Presence of any existing mental health issues, assessed using CORE-10. Participants who reveal potential mental health issues will be advised that we will write to their GP informing them of the results of the questionnaire 3. Quality of life, assessed using SF36 4. Current mood at time of assessment, assessed using Self-Assessment Mannikin (SAM) 5. Disease-specific issues, assessed using UPDRS & SAQ

—

Countries

England, United Kingdom

Contacts

Public ContactCharles Nduka

cnduka@gmail.com+44 (0)7957 561544

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026