Skip to content

Analgesia in acute injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN21732767
Enrollment
Unknown
Registered
2004-09-30
Start date
2003-06-19
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, lower leg injury Injury, Occupational Diseases, Poisoning Other and unspecified injuries of lower leg

Interventions

Patients will be randomised to receive either rofecoxib or diclofenac at the triage area. They will have regular objective and subjective pain and functional assessments and will be treated in the dep

Sponsors

Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients presenting to the emergency department with acute lower limb injuries. These must be less than 48 hours old and only include non-penetrating injuries with a pain score of 40 mm or more on a 100 mm Visual Analogue Scale (VAS).

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

MeasureTime frame
The main outcome measure is the change in VAS score over time after the initial dose of study medication over the next 4 hours.

Secondary

MeasureTime frame
Secondary outcome measures are twice daily patient's global assessments of pain and VAS score. There will be a modified SF-36 to complete on day 5.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026