Crohn's disease Digestive System Crohn's disease
Conditions
Interventions
The trial objective is to describe the impact upon motivation to stop smoking of using genotype to assess risk of developing Crohn's disease. We will compare the impact of risk assessment based on fam
Sponsors
King's College London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. First degree relatives of patients with Crohn's disease 2. Aged over 18 years 3. Living in the British Isles 4. Without a diagnosis of Crohn's disease or ulcerative colitis 5. Male or female 6. Smoke 5 or more cigarettes daily 7. Able to give informed consent to participate 8. Able to complete, either alone or with assistance, the study questionnaires
Exclusion criteria
Exclusion criteria: Those not meeting the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome as of 28/04/2008: Stopping smoking for 24 hours or longer in the six months following provision of risk information. Previous primary outcome: The proportion of participants in each group engaging in 1 or more quit-related behaviours, measured 6 months after participants are presented with their personalised risk information. | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportion of participants in each group who make smoking quit attempts of 6 or more days duration. This will be validated using questionnaires and biochemical indices. | — |
Countries
United Kingdom
Outcome results
None listed