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UPBEAT-UK: Case Management for depression and coronary heart disease

UPBEAT-UK: A pilot randomised controlled trial of case management for depressed primary care patients with symptomatic coronary heart disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN21615909
Enrollment
60
Registered
2010-04-22
Start date
2010-03-15
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease/comorbid depression Circulatory System Other acute ischaemic heart diseases

Interventions

Experimental intervention (usual care plus case management): The intervention will be case management delivered by two clinically qualified researchers (a community psychiatric nurse and a health psyc

Sponsors

King's College London (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Practices: 1. Keep a register of patients with CHD for the Quality and Outcomes Framework (QOF) 2. Willing to liaise over patients in the case management arm when necessary Participants: 1. Symptomatic CHD as scored on the modified Rose Angina Questionnaire 2. Score greater than 9 on the Hospital Anxiety and Depression Scale (HADS) 3. Aged 16 years or over, either sex

Exclusion criteria

Exclusion criteria: Patients: 1. Temporary registrations 2. Actively suicidal or experiencing psychotic depression as evidenced by delusions and/or hallucinations 3. Under the care of secondary care mental health teams 4. Cannot speak English 5. Currently in hospital for treatment of their CHD

Design outcomes

Primary

MeasureTime frame
Since this is a pilot study, an aim is to identify appropriate primary and secondary outcome measures. The following measures will be tested: 1. Depression (HADS, 9-item Patient Health Questionnaire [PHQ-9]) 2. Coronary Heart Disease (Modified Rose Angina Questionnaire, Specific Activity Schedule) 3. Quality of Life (Euroqol 5D, 12-item Medical Outcomes Survey Short Form [SF-12]) 4. Adherence to medication (Adapted version of Morisky adherence questionnaire) 5. Life events (List of Threatening Events Questionnaire) 6. Social problems (Social Problems Questionnaire) 7. Health Service Utilisation (Client Service Receipt Inventory (CSRI)) 8. Illness Perceptions (Brief Illness Perceptions Questionnaire) 9. Participants' problem priorities (Psychlops) Assessments will be at 1, 6 and 12 months for all outcomes.

Secondary

MeasureTime frame
No secondary outcome measures

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 26, 2026