The effect of intranasal sodium cromoglycate on symptoms of suspected acute viral upper respiratory tract infection (URTI) in children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN21562211

Enrollment

300

Registered

2000-10-23

Start date

1999-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary care Respiratory Upper respiratory tract infection

Interventions

300 children will be randomised to receive either normal saline nose spray or sodium cromoglycate 4% nose spray every 2 h (during waking hours) for the first 2 days, and every 4 h for a further 5 days

Eligibility

Inclusion criteria

Inclusion criteria: Children aged from 6 months to 6 years with suspected acute viral URTI for less than 36 h

Exclusion criteria

Exclusion criteria: Children with: a history of having taken cromolyns or steroids within the previous week; carers who are incapable of giving informed consent or unable to keep symptom diaries; an established complication requiring immediate hospitalisation, or for whom the clinician plans to prescribe antibiotics at the first consultation.

Design outcomes

Primary

Measure	Time frame
CARIFS Scale Score	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026