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Effect of vitamin D treatment on the improvement of metabolic syndrome

Effect of vitamin D treatment on the improvement of metabolic syndrome: a randomized single-blind trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN21527585
Enrollment
600
Registered
2012-01-16
Start date
2012-01-01
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome Nutritional, Metabolic, Endocrine Metabolic disorder, unspecified

Interventions

Anthropometric measures (weight, height, waist circumference) and blood pressure will be measured on all participants. A fasting blood sample will be collected for measurement of serum 25-hydroxy vita

Sponsors

Shandong University (China)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Male and female participants 2. Aged 35-60 years old 3. Living in Jinan, China for more than 5 years 4. Employed in an office setting 5. Has had more than 13 years of education

Exclusion criteria

Exclusion criteria: 1. Use of vitamin D and calcium supplementation within 60 days of screening 2. Current use of cigarettes (self-report) 3. Alcohol abuse (defined as >14 drinks/week for men, >7 drinks/week for women) 4. Diagnosis of overt diabetes, cardiovascular disease or other systematic disease 5. Use of medications that influence vitamin D, glucose, lipid profiles or blood pressure 6. Engaging in more than 20 minutes of strenuous physical activity or exercise that causes excessive breathing and sweating more than once per week

Design outcomes

Primary

MeasureTime frame
1. Weight, height, waist circumference and blood pressure 2. Body mass index (BMI) 3. Serum 25(OH)D and insulin, measured by double antibody radioimmunoassay 4. Plasma glucose, triglycerides, and HDL cholesterol, measured by enzymatic colorimetric assay

Secondary

MeasureTime frame
LDL cholesterol, calculated using the Friedwald equation

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026