Fever Signs and Symptoms
Conditions
Interventions
Unblinded but RCT. Children presenting at the children's emergency department with fever will be invited to take part. Those with a temperature greater than or equal to 38.0 degrees C will be enrolled
Sponsors
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Children presenting in the BRI children's emergency department with fever. Inclusion criteria: 1. Age 6 months - 16 years 2. Children with a temperature of 38.0 degrees C or more will be eligible
Exclusion criteria
Exclusion criteria: 1. Those admitted directly to resuscitation by ambulance or those transferred there following initial clinical assessment 2. Those eligible for recruitment in any other study running concurrently or those who have been recruited to a simultaneous study of children's fever 3. Prior administration that will interfere with randomisation: paracetamol within the last six hours or ibuprofen within the last six hours 4. Allergy to either study drug 5. Likely dehydration, cellulitis or skin infection, concomitant warfarin or heparin, chronic illness likely to interfere with drug metabolism (kidney or liver disease), immunosuppression, HIV+, concomitant chemo or radiotherapy, organ or bone marrow transplant recipient, immunosuppressive therapy in the last three months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The child's temperature one hour after study antipyretics | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed