Topic: Reproductive Health and Childb, Generic Health Relevance and Cross Cutting Themes
Conditions
Interventions
1. Deferred cord clamping: clamping the cord after at least two minutes
2. Immediate cord clamping: clamping the cord within 20 seconds
Sponsors
Nottingham University Hospitals NHS Trust (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women likely to have a live birth before 32 weeks gestation, regardless of mode of birth or whether cephalic or breech presentation
Exclusion criteria
Exclusion criteria: 1. Monochorionic twins (from an ultrasound scan) or clinical evidence of twin-twin transfusion syndrome 2. Triplets or higher order multiple pregnancy 3. Known congenital malformation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility outcomes for the original pilot trial: 1. Number of women recruited in each hospital 2. Proportion of potentially eligible women recruited 3. Reasons for non-recruitment (medical, parental, logistic, other) 4. Spectrum of gestational age and neonatal outcome among recruits 5. Compliance with the trial interventions, and reasons for non-compliance 6. Completeness of data collection for main outcomes 7. Views of women and their partners on recruitment, randomisation and the interventions 8. Proportion lost to follow up after discharge from hospital, and reasons for loss to follow up Added 01/07/2016: As the primary outcomes planned for the main Cord Trial were death and intraventricular haemorrhage, these were the pre-specified main outcomes for the analysis by allocated group for the Cord Pilot Trial. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
United Kingdom
Outcome results
None listed