The effect of Roux-en-Y bariatric surgery on early and late cardiovascular risk markers in patients with obesity

The effect of Roux-en-Y bariatric surgery on early and late cardiovascular risk markers in patients with obesity: an observational prospective study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN21400062

Enrollment

Registered

2009-05-13

Start date

2009-04-14

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

Patients will be seen before surgery and then at 3 monthly intervals for 12 months after surgery. At each visit fasting bloods will be taken to determine insulin resistance along with fibrin structure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Both males and females, over age of 16 years 2. Body Mass Index greater than 40 kg/m^2, or greater than 35 kg/m^2 with comorbidity 3. To have Roux-en-Y bariatric surgery 4. Able to give informed consent 5. Consent to inform their GP's regarding their participation in the study 6. No changes to medication in last 3 months 7. Smokers can be included

Exclusion criteria

Exclusion criteria: Patients not wishing disclosure to their GP's.

Design outcomes

Primary

Measure	Time frame
To show that Roux-en-Y surgery significantly improves endothelial function.	—

Secondary

Measure	Time frame
To illustrate that bariatric surgery improves fibrin clot structure and function.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026