Pain following photorefractive keratectomy procedure Surgery
Conditions
Interventions
The patients are randomized using computer-generated randomization tables to three groups: topical nalbuphine postoperative with a concentration of 2 mg/ml (group A), topical nalbuphine with a concent
Sponsors
Delta Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age above 20 years 2. Error of refraction is less than 4 D spherical equivalent 3. Minimum corneal thickness is more than 480 microns 4. Absence of collagen diseases 5. Absence of corneal surface abnormalities 6. Absence of ocular diseases other than the refractive error 7. No history of concurrent use of systemic or topical analgesics
Exclusion criteria
Exclusion criteria: 1. Age below 20 years 2. Error of refraction is more than 4 D spherical equivalent 3. Minimum corneal thickness is less than 480 microns 4. Presence of collagen diseases 5. Presence of corneal surface abnormalities 6. Presence of ocular diseases other than the refractive error 7. History of concurrent use of systemic or topical analgesics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain measured using a numeric rating scale (recording the maximum pain level) in the first 3 postoperative days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of analgesic eye drops applications recorded by patients in the first 3 postoperative days 2. Time needed for complete epithelial healing assessed by slit-lamp examination daily in the first 8 postoperative days 3. Best corrected visual acuity (converted to LogMAR) measured by Landolt chart at the end of the third postoperative month 4. Refraction measured by autorefractometer at the end of the third postoperative month | — |
Countries
Egypt
Outcome results
None listed