Diagnosis of Pulmonary Embolism in Pregnancy (DiPEP)

Diagnosis of pulmonary embolism in pregnancy: a case-control study, biomarker study and decision-analysis modelling of effectiveness, cost-effectiveness and value of information

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN21245595

Enrollment

420

Registered

2014-07-14

Start date

2014-10-01

Completion date

Unknown

Last updated

2018-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary embolism in pregnancy Circulatory System Pulmonary embolism

Interventions

The study will be testing clinical predictors and biomarkers for PE, and diagnostic strategies (including clinical prediction rules) used to select pregnant or postpartum women for imaging. Data will

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Pregnant and postpartum women with diagnosed PE from all UK hospitals over 18 months 2. Pregnant and postpartum women with suspected PE or diagnosed DVT from 8 hospitals over 18 months

Exclusion criteria

Exclusion criteria: 1. Women who did not present with suspected PE 2. Women who are unable to consent, requiring resuscitation or with an existing diagnosis of PE

Design outcomes

Primary

Measure	Time frame
1. Pulmonary embolism (PE) 2. Cost-effectiveness The outcome for diagnostic accuracy (case-control) study will be diagnosis of PE based on diagnostic imaging and any adverse events up to 30 days. The outcome for the cost-effectiveness analysis will be life-time quality-adjusted life years (QALYs), estimated by decision analysis modelling.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026