Electro-acupuncture for prolonged disorders of consciousness

Clinical efficacy of electro-acupuncture stimulation based on mismatch negativity in patients with prolonged disorders of consciousness

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN21011105

Enrollment

Registered

2026-02-06

Start date

2024-04-01

Completion date

Unknown

Last updated

2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To investigate the clinical effectiveness of electro-acupuncture at Cuanzhu (BL 2) and Sibai (ST 2) acupoints in individuals with prolonged disorders of consciousness and assess the therapeutic impact of arousal therapy on such patients. Signs and Symptoms

Interventions

Rehabilitation nursing focused on optimising limb positioning and managing artificial airways. Rehabilitation techniques included joint range-of-motion exercises and breathing training. In addition t

Eligibility

Sex/Gender

All

Age

50 Years to 66 Years

Inclusion criteria

Inclusion criteria: 1. Fulfill the requirements for a chronic DOC diagnosis 2. Perform CT or magnetic resonance imaging scans to confirm that the patient has brain trauma, cerebral hemorrhage or cerebral infarction, etc 3. Sign the informed permission form

Exclusion criteria

Exclusion criteria: 1. Known hearing impairment 2. History of severe cardiopulmonary diseases or other neurological disorders 3. Metal implants that may interfere with EEG or electro-acupuncture treatment 4. Taking sedative-hypnotic drug intake during the MMN test 5. Incomplete clinical data or loss to follow-up 6. Presence of skin damage at the electrode placement site

Countries

China

Contacts

Public ContactXuehai Lv

zxyylvxuehai@126.com+86 18931032102

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026