Tendinopathy is a general term for chronic tendon pain. the etiology is almost unknown. Despite of inflammation like symptoms, no inflammatory cells seem to be present in the disease. Injury, Occupational Diseases, Poisoning Injury of Achilles tendon
Conditions
Interventions
Thirty patients with chronic Achilles tendon pain were randomly assigned to either a Structural study (n=14) or a Biochemical study (n=16) by the envelope method.
Blood samples
Blood samples taken fr
Sponsors
Center for Healthy Aging, University of Copenhagen [Center for Sund Aldring] (Denmark)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with chronic tendon pain for more than 6 months
Exclusion criteria
Exclusion criteria: Patients who had received steroid injections less than 6 months ago
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Structural parameters: fibril density, fibril size, volume fraction of cells and the nucleus/cytoplasm ratio of cells were determined (measured at baseline) 2. Further gene expressions of various genes were analyzed including markers for collagen synthesis, collagen degradation, inflammation, wound healing, pain and fibrillogenesis (measured at baseline) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Visa A score 2. Activity levels 3. BMI calculations 4. Ultrasound and elastography analysis | — |
Countries
Denmark
Outcome results
None listed