High-frequency radio-wave electrosurgery versus simple conjunctival resection for conjunctivochalasis

A prospective study comparing the efficacy of high-frequency radio-wave electrosurgery versus simple conjunctival resection for treatment of conjunctivochalasis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN20773574

Enrollment

Registered

2016-12-08

Start date

2013-03-19

Completion date

Unknown

Last updated

2018-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Conjunctivochalasis Eye Diseases

Interventions

1 = some of the time

2 = half of the time

3 = most of the time

Patients are randomized into two groups according to their medical record numbers. The even numbers receive high-frequency radio-wave electrosurgery (Group I) and the odd numbers receive simple conjun

Grade 1 = a single, small fold

Grade 2 = ? 2 folds, but not higher than the tear meniscus

Grade 3 = multiple folds and higher than the tear meniscus) proposed by Meller and Tseng. Grading is done separately for the temporal, middle, and nasal areas of the conjunctiva. Epiphora and dry eye

Allergan, Inc., Irvine, CA,) a 12-item questionnaire designed to assess the severity of symptoms. The 12 items of the OSDI questionnaire are graded on a scale of 0 to 4: 0 = never

and 4 = all the time. The total OSDI score is then calculated with the following formula: OSDI = ([sum of scores for all questions answered] x 100)/([total number of questions answered] x 4). Thus, th

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 50 to 100 with symptomatic CCh 2. Willing to receive surgical treatment

Exclusion criteria

Exclusion criteria: 1. History of conjunctival surgery 2. Nasolacrimal duct obstruction 3. Without consent

Design outcomes

Primary

Measure	Time frame
1. Conjunctivochalasis, assessed by slit lamp examination using the grading system proposed by Meller and Tseng at baseline, 1 week, 1 month, 3 months and 6 months 2. Dry eye symptoms, assessed with the Ocular Surface Disease Index (OSDI) score at baseline, 3 months and 6 months	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026