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INpatient and Day-clinic treatment for DEPression: who profits well and who don´t?

INpatient and Day-clinic treatment for DEPression: symptom course and response prediction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN20317064
Enrollment
600
Registered
2012-07-31
Start date
2011-03-01
Completion date
Unknown
Last updated
2020-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depression (inpatient and day clinic treatment) Mental and Behavioural Disorders Depressive episode

Interventions

We include all patients who are consecutively admitted to the study centres over a period of 2.5 years. To compare inpatient and day clinic treatment (especially differences in predictors of symptom c

Sponsors

Heidehof Foundation Ltd. (Heidehof Stiftung GmbH) (Germany)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Major depressive episode (MDE), unipolar, according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) as main diagnosis 2. Age 18-65 years 3. Quick Inventory of Depressive Symptomatology (QIDS)-expert rating score > 10 4. Informed consent

Exclusion criteria

Exclusion criteria: 1. Psychotic disorder 2. Bipolar disorder 3. Substance abuse (current or last three years) 4. Current suicidal ideation 5. Antisocial personality disorder 6. Cognitive impairment 7. Admission for diagnostic reasons (not for treatment) 8. Second admission during recruitment period

Design outcomes

Primary

MeasureTime frame
Depressive symptomatology, assessed with the QIDS-C (Quick-Inventory of Depressive Symptomatology, expert rating) at pre, post and follow-ups (3 and 12 month after discharge) 1. Change in symptoms will be assessed: 1.1. Dimensional (change in QIDS-score) 1.2. Categorial: reduction 50=partial remission; falling below the cut-off for depression=complete remission)

Secondary

MeasureTime frame
1. Global severity index (GSI), Symptom-Check-List-90-R 2. Social and Occupational Functioning Assessment Scale (SOFAS) 3. Quality of Life SF-12 Predictor analyses include: 1. Symptomatology (characteristics of depression, co-morbodity, axis-II-diagnoses) and overall disturbance 2. Demographics 3.Personality and interpersonal problems (DEQ: Depressive Experience Questionnaire; DAS: Dysfunctional Attitudes Scale; IIP: Inventory of Interpersonal Problems) 4. Traumatization (CTQ: Childhood-Trauma-Questionnaire) Follow up: 3 and 12 months after discharge.

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 24, 2026