Major Depression (inpatient and day clinic treatment) Mental and Behavioural Disorders Depressive episode
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Major depressive episode (MDE), unipolar, according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) as main diagnosis 2. Age 18-65 years 3. Quick Inventory of Depressive Symptomatology (QIDS)-expert rating score > 10 4. Informed consent
Exclusion criteria
Exclusion criteria: 1. Psychotic disorder 2. Bipolar disorder 3. Substance abuse (current or last three years) 4. Current suicidal ideation 5. Antisocial personality disorder 6. Cognitive impairment 7. Admission for diagnostic reasons (not for treatment) 8. Second admission during recruitment period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depressive symptomatology, assessed with the QIDS-C (Quick-Inventory of Depressive Symptomatology, expert rating) at pre, post and follow-ups (3 and 12 month after discharge) 1. Change in symptoms will be assessed: 1.1. Dimensional (change in QIDS-score) 1.2. Categorial: reduction 50=partial remission; falling below the cut-off for depression=complete remission) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Global severity index (GSI), Symptom-Check-List-90-R 2. Social and Occupational Functioning Assessment Scale (SOFAS) 3. Quality of Life SF-12 Predictor analyses include: 1. Symptomatology (characteristics of depression, co-morbodity, axis-II-diagnoses) and overall disturbance 2. Demographics 3.Personality and interpersonal problems (DEQ: Depressive Experience Questionnaire; DAS: Dysfunctional Attitudes Scale; IIP: Inventory of Interpersonal Problems) 4. Traumatization (CTQ: Childhood-Trauma-Questionnaire) Follow up: 3 and 12 months after discharge. | — |
Countries
Germany