Knee osteoarthritis Musculoskeletal Diseases Osteoarthritis (OA)
Conditions
Interventions
A six-week high-intensity supervised exercise session twice a week, or a non-intervention control group.
Sponsors
The Swedish Rheumatism Association (Sweden)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 35 - 65 years 2. Living in a defined geographic area 3. Diagnosis of radiographic knee osteoarthritis according to Kellgren & Lawrence grade III or more (i.e joint space narrowing and definite osteophytes)
Exclusion criteria
Exclusion criteria: 1. Inflammatory joint disease 2. Anterior cruciate ligament injury 3. Known symptomatic injury to the menisci 4. Hip symptoms more aggravating than the knee symptoms 5. About to have knee replacement surgery within 6 months 6. Co-morbidities not allowing exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee injury and Osteoarthritis Outcome Score (KOOS, a disease specific questionnaire, assessing pain, other symptoms, activities of daily living, sport and recreation function and knee-related quality of life). Time points of interest were 6 weeks and 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. 36-item short form health survey (SF-36, a generic measure of general health status) 2. Five tests of functional performance: 2.1. Åstrands bicycle-ergometre test 2.2. Rising on one leg from sitting on lowest possible height 2.3. One-leg hop 2.4. Lateral step-up 2.5. One-leg semi squatting 2.6. Heel-rising on one leg | — |
Countries
Sweden
Outcome results
None listed