Post-tuberculosis disease Infections and Infestations
Conditions
Interventions
To address Objective 1 (post-TB care needs assessment) and Objective 2 (post-TB care package) our Target Populations are TB survivors and post-TB care providers from South Africa and Cambodia, Setting
Sponsors
London School of Hygiene & Tropical Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Completed TB treatment, or 2. Providing care for TB patients
Exclusion criteria
Exclusion criteria: Current TB
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective 1: Post-TB Care Assessment 1. Severity of biological impairment is measured using radiological imaging (e.g. chest X-ray or CT), spirometry, and cardiopulmonary exercise testing over 12 months 2. Severity of psychosocial impairment is measured using extended questionnaires including validated mental health and quality of life scales (e.g. PHQ-9, GAD-7, WHOQOL-BREF) over 12 months 3. Severity of economic impairment is measured using structured economic impact questionnaires (e.g. household income, employment status, healthcare expenditure) over 12 months 4. Predictive accuracy of the operational assessment tool is measured using ROC curves and C-statistics comparing tool outputs to reference standard assessments over 12 months 5. Informative items for psychosocial and economic assessment are identified using predictive modelling of questionnaire responses over 12 months Objective 2: Post-TB Care Package 6. Patient preferences for post-TB care are measured using qualitative interviews and Discrete Choice Experiments 7. Provider preferences for post-TB care are measured using qualitative interviews and Discrete Choice Experiments 8. Acceptability and feasibility of post-TB care package is measured using thematic analysis of qualitative interview data from patients and providers 9. Preference heterogeneity in post-TB care is measured using Multinomial Logit and Latent Class models applied to Discrete Choice Experiment data | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
Cambodia, South Africa
Contacts
Public ContactRein Houben
Outcome results
None listed