Major depressive disorders Mental and Behavioural Disorders
Conditions
Interventions
1. Intervention group: Psychotherapy plus web-based online platform (deprexis):
Participants in the intervention group receive access to the deprexis platform. Trained, certified psychotherapists int
Sponsors
Swiss National Science Foundation (Switzerland)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: We include adults 1. Aged 18 or over 2. Suffer from a MDD according to the International Classification of Diseases (ICD-10; i.e., F32.-depressive episode, F33.- Recurrent Depressive Disorder, F34.- Persistent Affective Disorder, F38.- Other Affective Disorder, F39 Unspecified Affective Disorder) 3. Who have a Beck Depression Inventory (BDI-II) sum score over 13 4. Who have sufficient knowledge of the German language 5. Who have Internet access and sufficient knowledge to use it (based on self-report) 6. Who are willing to give informed consent
Exclusion criteria
Exclusion criteria: We will exclude subjects who: 1. Have a known psychotic or bipolar disorder 2. Suffer from a chronic depression with onset in childhood (based on clinical judgment) 3. Show a notable suicidal risk (based on clinical judgment of the therapists)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depressive symptomatology as measured with the Beck Depression Inventory (BDI-II). Timepoints of assessment: pretreatment, posttreatment (12 weeks), follow-up (6 months) | — |
Secondary
| Measure | Time frame |
|---|---|
| Measures 1 to 7 are assessed at pretreatment, posttreatment (12 weeks), and at follow-up (6 months) 1. Symptoms of anxiety assessed with the German version of the 7-item Generalized Anxiety Disorder Scale (GAD-7) 2. Somatic symptomatology as assessed with the somatic symptom module of the Patient Health Questionnaire (PHQ) 3. Quality of life assessed with the Short-Form Health Survey-12 (SF-12) 4. Questionnaire for the evaluation of psychotherapeutic progress (FEP-2) to measure the dimensions well-being, symptoms, interpersonal relationships, and incongruence with respect to approach and avoidance goals 5. Web Screening Questionnaire (WSQ) to screen for common mental disorders. The WSQ is a 15-item self-report instrument screening for frequent mental disorders 6. Suicidal tendencies as assessed with the Suicidal Behaviours Questionnaire-Revised (SBQ-R) 7. Psychological empowerment as assessed with an adapted version of the scale by Spreitzer 8. Depression diagnosis as assessed by the licenced therapists conducting the treatment (only pre-and posttreatment) 9. Working Alliance Inventory ? Short (WAI-S; adapted version) as assessed by patients and therapists (week 6; week 12) | — |
Countries
Germany
Outcome results
None listed