Prevention of non-communicable diseases in the next generation Other
Conditions
Interventions
The study is a community-based, cluster-randomised intervention with three arms (preconception, pregnancy and control), with individual villages forming the basis for the cluster. Women in all three a
Sponsors
CSI Holdsworth Memorial Hospital
Vivekananda Memorial Hospital
University of Toronto
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Women of childbearing age 2. Over the age of 18 years 3. Married 4. No children or one child 5. Planning to have a child within the next 2 years
Exclusion criteria
Exclusion criteria: Current exclusion criteria as of 18/12/2025: Those who are not planning pregnancy or have already completed their family or undergone sterilisation. Previous exclusion criteria: Those with two or more children
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adiposity measured by fat mass index (fat mass/height²) using dual x-ray absorptiometry (DXA) at age 5 years in the children across all HeLTI cohorts | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured in the children at age 5 years: 1. Overweight and obesity (OWO) assessed by BMI and indicators of body composition and distribution (waist circumference, skinfold thickness) 2. Glucose metabolism measured by fasting venous plasma glucose concentration 3. Resting systolic blood pressure measured using an automated blood pressure monitor 4. Child development assessed using modified Kaufman battery, validated for Indian settings | — |
Countries
India
Contacts
Public ContactKiran Nagaraj
Outcome results
None listed