Palliative pylorus-preserving pancreatic head resection and postoperative chemotherapy versus primary chemotherapy alone for patients with advanced carcinoma of the pancreatic head

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN20060588

Enrollment

Registered

2007-07-02

Start date

2003-09-15

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic head carcinoma Cancer Pancreatic head carcinoma

Interventions

Group 1: standard pylorus-preserving pancreatic head resection with regional lymphadenectomy (this is an internationally well accepted surgical procedure) and after completion of wound healing (up to

Eligibility

Inclusion criteria

Inclusion criteria: Medical centres experienced in surgical and medical care of patients with pancreatic head carcinoma.

Exclusion criteria

Exclusion criteria: No exclusion criteria.

Design outcomes

Primary

Measure	Time frame
Survival, measured after 3, 6 and 12 months	—

Secondary

Measure	Time frame
1. Quality of life, measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for Cancer patients (EORTC QLQ-C30) and the EORTC Quality of Life Questionnaire for Pancreatic cancer (QLQ PAN26). This will be measured after 3, 6 and 12 months 2. Surgical complications, measured after 3, 6 and 12 months 3. Toxicity of chemotherapy, measured after 3, 6 and 12 months	—

Measure

Time frame

1. Quality of life, measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for Cancer patients (EORTC QLQ-C30) and the EORTC Quality of Life Questionnaire for Pancreatic cancer (QLQ PAN26). This will be measured after 3, 6 and 12 months 2. Surgical complications, measured after 3, 6 and 12 months 3. Toxicity of chemotherapy, measured after 3, 6 and 12 months

—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026