24-hour electrocardiogram profiles during acetate-free biofiltration with constant and potassium-profiled dialysate

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN20002762

Enrollment

Registered

2006-07-14

Start date

2003-02-24

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrhythmia Circulatory System Cardiac arrhythmia

Interventions

Dialysis with AFB potassium-profiled (AFBK) dialysis versus constant constant AFB. In both AFB and AFBK, AN69ST haemofilter (same size as used run in period) will be used. Blood and dialysate flow rat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. End stage renal disease (ESRD) patients 2. Duration of renal replacement therapy (RRT) for at least the last six months 3. Three times a week dialysis schedule 4. Patients who, at the time of admission to the study, are being treated with bicarbonate dialysis 5. Age greater than 18 years old

Exclusion criteria

Exclusion criteria: 1. Patients older than 80 years 2. Patients on antiarrhythmogenic treatment or antihypertensive treatment, which have a declared effect on cardiac rhythm 3. Patients receiving pacemaker or cardiac stimulator 4. Patients on variable digitalis dosage 5. Patients in hypokalemia

Design outcomes

Primary

Measure	Time frame
Aim of the study is to evaluate the efficacy of AFB potassium-profiled dialysis in the reduction of the number of cardiac arrhythmias during the treatment, compared to constant potassium AFB.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

France, Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026