Neuroscience, psychiatry Nervous System Diseases Intracerebral haemorrhage
Conditions
Interventions
Early surgical evacuation/initial conservative treatment
Sponsors
Medical Research Council (MRC) (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Spontaneous, supratentorial intracerebral haemorrhage within 72 h and uncertainty about surgery 2. Minimum clot diameter of 2 cm on initial Computed Tomography (CT) 3. Glasgow Coma Score of 5 or above
Exclusion criteria
Exclusion criteria: 1. Haemorrhage due to aneurysm or arteriovenous malformation 2. Cerebellar or brainstem haemorrhages or brainstem extensions of a supratentorial haemorrhage 3. ICH secondary to a tumour or trauma 4. Where surgery cannot be performed within 24 h of randomisation 5. Evidence of severe pre-existing physical or mental disability or of severe co-morbidity which might interfere with the assessment of outcome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glasgow Outcome Scale (favourable = GR/MD: unfavourable = SD/V/D)/ Rankin & Barthel Scale/Mortality | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed