The use of high frequency oscillator ventilation (HFOV) in paediatric acute respiratory distress syndrome (ARDS) with open lung technique

The use of high frequency oscillator ventilation (HFOV) in paediatric acute respiratory distress syndrome (ARDS) with open lung technique: a prospective, interventional open label trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN19924570

Enrollment

Registered

2009-09-07

Start date

2007-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Paediatic acute respiratory distress syndrome (ARDS) Respiratory Respiratory failure, not elsewhere classified

Interventions

Recruitment protocol: Body weight less than 35 kg (use of 3100 A): 1. Select patient (central line and/or arterial lines were placed prior to the manouevre) 2. Stable VS (optimised preload/use of ino

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Paediatric patients aged greater than 1 month to less than 15 years old (from January 2007 - November 2008), either sex 2. Diagnosis of ARDS within 72 hours of Paediatric Intensive Care Unit (PICU) admission 3. No exclusion criteria

Exclusion criteria

Exclusion criteria: 1. Pulmonary capillary wedge pressure greater than or equal to 18 mmHg 2. Evidence of left atrial hypertension 3. Severe irreversible neurological injury or intractable shock 4. The underlying disease was deemed irreversible or ARDS greater than 48 hours 5. Pre-existing air leak syndrome (e.g., pneumothorax or pneumomediastinum) 6. Pre-existing cystic lung disease

Design outcomes

Primary

Measure	Time frame
Oxygenation response, measured at 28 days in PICU	—

Secondary

Measure	Time frame
Mortality, measured at 28 days in PICU	—

Countries

Thailand

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026