Infants at risk of undernutrition Nutritional, Metabolic, Endocrine Infants at risk of undernutrition
Conditions
Interventions
Four different pre-cooked complementary food supplements given as a porridge daily from 6-15 months of age (6-8 months: 50 g, 9-12 months: 75 g, 13-15 months: 125 g)
1. WinFood CF: rice and two highly
Sponsors
University of Copenhagen (Denmark)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Children who are 6 months old and have a weight-for-height z-score > -3
Exclusion criteria
Exclusion criteria: 1. Weight-for-height z-score < -3 2. Bilateral pitting oedema 3. Haemoglobin (Hb) < 80 g/L 4. Clinical signs of vitamin A deficiency (xerosis or Bitot spots). These children will be referred for treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in fat-free body mass (deuterium dilution) and iron status (serum ferritin and transferrin receptors) from baseline (age 6 months) until the end of the 9 month intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in: 1. Ponderal and linear growth 2. Physical activity (using an accelerometer, actigraph) 3. Motor milestones (questionnaire, clinic visits) 4. Morbidity 5. Haemoglobin concentration (using Haemocue) 6. Serum concentrations of acute phase proteins [C-reactive protein (CRP) and a-acid glycoprotein(AGP)], insulin-like growth factor (IGF)-1 and zinc 7. Whole blood fatty acid composition Measured from baseline (age 6 months) until the end of the 9 month intervention | — |
Countries
Cambodia
Outcome results
None listed